Phenyl Dichorophosphate

Phenyl Dichorophosphate

CAS NO:770-12-7

Manufacture site:Ruyu
Spec:In-house. Batch size:1000kg. Annual capacity:200mt

Chemical Name	Phenyl Dichlorophosphate
Synonyms	Phosphorodichloridic Acid Phenyl Ester; Phenyl Phosphorodichloridate; Dichlorophenoxyphosphine Oxide; NSC 44412; Phenoxydichlorophosphine Oxide; Phenoxyphosphoryl Dichloride; Phenyl Dichlorophosphinate; Phenylphosphoric Dichloride
CAS Number	770-12-7
Molecular Formula	C₆H₅Cl₂O₂P
Appearance	Colourless Oil
Melting Point	N/A
Molecular Weight	210.98
Storage	Hygroscopic, Refrigerator, under inert atmosphere
Solubility	Chloroform
Stability	Moisture Sensitive
Category	Building Blocks; Miscellaneous;
Applications	Phenyl Dichlorophosphate is used as a reagent in the synthesis of aspartic acid based nucleoside phosphoramidate prodrugs as potent inhibitors of hepatitis C virus replication. Also a reagent in the synthesis of nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as inhibitors of HCV NS5B polymerase.

Precautionary statement(s).
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P310+P330+P331 If swallowed: Immediately call a POISON CENTER or doctor/physician. Rinse mouth.
Do NOT induce vomiting.
P303+P361+P353+P310 If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse
skin with water/shower. Immediately call a POISON CENTER or doctor/physician. P304+P340+P310 If inhaled: Remove victim to fresh air and keep at rest in a position comfortable for breath-
ing. Immediately call a POISON CENTER or doctor/physician. P305+P351+P338+P310 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do, continue rinsing. Immediately call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to an approved waste disposal plant.
Handling and storage
Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electro-
static charge. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent
leakage.
 Specific end use(s): Laboratory chemicals, for scientific research and development only.