China Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Manufacturers, Suppliers and Factory

Product Description

Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate. CAS NO:769195-26-8

Usage:Sitagliptin Intermediates

Chemical Name	Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
Synonyms	2,4,5-Trifluoro-β-oxo-benzenebutanoic Acid Methyl Ester
CAS Number	769195-26-8
Molecular Formula	C₁₁H₉F₃O₃
Appearance	Pale Yellow to Light Yellow Solid
Melting Point	41 - 43ºC
Molecular Weight	246.18
Storage	Refrigerator
Solubility	DMSO (Slightly), Methanol (Slightly)
Category	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate is a useful synthetic intermediate in the synthesis of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase (DPP) IV inhibitor for the treatment of type II diabetes.

Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.