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New Products
2-Cyanobenzyl Bromide
2-Cyanobenzyl Bromide CAS NO:22115-41-9 Usage:Alogliptin Intermediates
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Product Description
2-Cyanobenzyl BromideCAS NO:22115-41-9
Usage:Alogliptin Intermediates
Chemical Name
2-(Bromomethyl)benzonitrile
Synonyms
α-Bromo-o-tolunitrile; (2-Cyanophenyl)methyl Bromide; 1-(Bromomethyl)-2-cyanobenzene; 2-(Bromomethyl)benzonitrile; 2-Cyano-a-bromotoluene; 2-Cyanobenzyl Bromide; o-(Bromomethyl)benzonitrile; o-Cyanobenzyl bromide; α-Bromo-2-cyanotoluene; α-Bromo-otolunitrile; α-Bromo-o-toluonitrile
CAS Number
22115-41-9
Molecular Formula
C₈H₆BrN
Appearance
Off-White to Pale Beige Solid
Melting Point
70-71°C
Molecular Weight
196.04
Storage
Refrigerator, under inert atmosphere
Solubility
Chloroform (Slightly), Ethyl Acetate (Slightly)
Category
Building Blocks; Miscellaneous;
Applications
2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
Pictogram
Signal Word
Danger
Hazard Statements
H302 : Harmful if swallowed.
H314 : Causes severe skin burns and eye damage.
Precautionary Statements
P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dusts or mists.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 : Wash contaminated clothing before reuse.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P405 : Store locked up.
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