Home > Products > Intermediates > (3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One
(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One
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(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One

Product Name:(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One CAS NO:32384-65-9
Molecular Formula:C18H42O6Si4
Formula Weight:466.87
Usage:Dapagliflozin Intermediates​

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Product Description

(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One

CAS NO:32384-65-9 

Usage:Dapagliflozin Intermediates


Chemical Name 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone
Synonyms (3R,4S,5R,6R)-3,4,5-Tri[(trimethylsilyl)oxy]-6-[[(Trimethylsilyl)oxy]methyl]tetrahydro-2H-pyran-2-one;
CAS Number 32384-65-9
Molecular Formula C₁₈H₄₂O₆Si₄
Appearance Colourless to Pale Yellow Oil
Melting Point N/A
Molecular Weight 466.86
Storage Refrigerator
Solubility Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone is an antidiabetic agent and an intermediate of Dapagliflozin (D185370). 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone acts as a reagent in the synthesis of trans-cyclohexane-bearing C-glucose as sodium glucose co-transporter 2 inhibitors.
HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Storage conditions: Refrigerator

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