Product Name:(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One
CAS NO:32384-65-9
Molecular Formula:C18H42O6Si4
Formula Weight:466.87
Usage:Dapagliflozin Intermediates
(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One
CAS NO:32384-65-9
Usage:Dapagliflozin Intermediates
HANDLING AND STORAGE
Chemical Name
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone
Synonyms
(3R,4S,5R,6R)-3,4,5-Tri[(trimethylsilyl)oxy]-6-[[(Trimethylsilyl)oxy]methyl]tetrahydro-2H-pyran-2-one;
CAS Number
32384-65-9
Molecular Formula
C₁₈H₄₂O₆Si₄
Appearance
Colourless to Pale Yellow Oil
Melting Point
N/A
Molecular Weight
466.86
Storage
Refrigerator
Solubility
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone is an antidiabetic agent and an intermediate of Dapagliflozin (D185370). 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone acts as a reagent in the synthesis of trans-cyclohexane-bearing C-glucose as sodium glucose co-transporter 2 inhibitors.
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Storage conditions: Refrigerator