(2S)-1-(Chloroacetyl)-2-Pyrrolidinecarbonitrile CAS NO:207557-35-5 Molecular Formula:C₇H₉ClN₂O Appearance:Pale Yellow to Light Brown Solid Melting Point:>60°C (dec.) Molecular Weight:172.61 Usage:Vildagliptin Intermediates
(2S)-1-(Chloroacetyl)-2-Pyrrolidinecarbonitrile CAS NO:207557-35-5
Usage:Vildagliptin Intermediates
Chemical Name
(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
Synonyms
(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile; (2S)-1-Chloroacetylpyrrolidine-2-carbonitrile; (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile; 1-Chloroacetyl-2-(S)-cyanopyrrolidine
CAS Number
207557-35-5
Molecular Formula
C₇H₉ClN₂O
Appearance
Pale Yellow to Light Brown Solid
Melting Point
>60°C (dec.)
Molecular Weight
172.61
Storage
Hygroscopic, Refrigerator, under inert atmosphere
Solubility
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category
Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications
(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin
Pictogram
Signal Word
Warning
Hazard Statements
H302 : Harmful if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H335 : May cause respiratory irritation.
Precautionary Statements
P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.